Pigmented Lesions: Clinical Pearls from Hensin Tsao, MD, PhD

  • For the diagnosis of melanoma, best procedure is excision with 2-3mm margins;
  • Treatment of primary melanoma is excision with 1-2cm margins;
  • Sentinel lymph node biopsy should be seriously considered in anyone with melanoma >1mm;
  • Interferon approved for Stage IIC and III melanoma;
  • Anti-BRAF and anti-MEK treatments highly effective for BRAF-mutated melanomas;
  • Checkpoint therapy exploding onto the scene.