Ilona J. Frieden, MD Sturge-Weber Update Sturge-Weber syndrome (SWS) is the triad of a port wine stain involving a V1 distribution as well as brain vascular malformations and often times glaucoma along with other ocular sequalae. A recent report, published in December of 2011, from the Brain Vascular Malformation Consortium and the Sturge-Weber Syndrome […]
In this presentation, Dr Friedlander discusses the many clinical applications of rapamycin, a target of the P13K pathway which was previously discussed by Dr Frieden. Is Rapamycin the new wonder drug for kids? Rapamycin (sirolimus) is an immunosuppressant used to prevent rejection. It is a macrolide and derives from a Streptomyces species. Rapamycin was first […]
In this presentation, Dr Frieden discusses molecular pathways and how the science can be applied into clinical practice in order to optimize the outcomes for patients with dermatologic diseases. The concept of Molecular Pathways Dr Frieden’s concept of molecular pathways is described here. Signaling pathways are essential in regulation and growth development. These pathways are […]
Suzanne L. Kilmer, MD Clinical Pearls: When Combining Devices with Injectables and Other Devices In this presentation, Dr Kilmer reviews the techniques for combining the various technologies that are currently available for facial rejuvenation in order to obtain optimal cosmetic improvement for patients. Dr Kilmer stresses the importance of remembering the 4 Rs: Relax Refill […]
John J. Zone, MD In general, Dermatologists see very few blistering diseases. Therefore, managing these autoimmune conditions can often be a challenge in practice. Dr Zone, an expert in the field of autoimmune blistering diseases, discusses these conditions and optimal strategies for managing these patients from his perspective. Dr Zone came upon this topic because […]
Pediatric Psoriasis Lawrence F. Eichenfield, MD Obesity appears to be a common comorbidity in pediatric patients with psoriasis. It is uncertain if the cardiovascular risks seen in adults with psoriasis is fundamentally related to obesity, skin inflammation, or other factors. It is reasonable to discuss these issues with families of children with psoriasis, though much […]
Inflammatory Disease in Little Kids Lawrence F. Eichenfield, MD In this presentation, Dr. Eichenfield discussed inflammatory diseases in children in a clinically relevant manner. Dr. Eichenfield provided a review of the pathogenesis of atopic dermatitis (AD), the role of filaggrin, and allergies in AD. He also updated us on new findings in pediatric psoriasis. […]
Diet and Acne & Rosacea Alan Shalita, MD In this presentation, Dr Shalita discusses the role of one’s diet and its relationship to acne and rosacea. Unfortunately, there is not a lot of information about diet and acne; however, there is a tremendous amount of interest in this subject. Dr Whitney Bowe conducted various aspects […]
POINT: COUNTERPOINT – MACE and Its Relationship to IL 12/23 Inhibition Ken Gordon, MD Dr. Gordon presented a counterpoint to Dr. Leonardi’s perspective regarding the association of IL 12/23 inhibition with MACE events. Dr. Gordon feels that while there is not a definitive answer at this time regarding the association it is important to discuss […]
Craig Leonardi, MD IL-12/23 Safety Issues Cardiovascular Safety in Psoriatics Using Biologic Drugs. Does a Signal Exist in the IL12/23 Pathway? Case Report MACE in a Ustekinumab-Treated Psoriasis Patient 47 year old construction worker Caucasian male Weight: 290 lbs Negative Hx: DM, HTN, Tobacco Psoriasis 20 yr history 15% BSA; PGA: M-S; DLQI: 12 No […]
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