Advanced Systemic and Topical Therapy in Pediatrics

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A few clinical pearls from Dr. Albert Yan’s presentation on Advanced Systemic and Topical Therapy in Pediatrics at the 2015 Fall NPPA conference:

  • N-acetylcysteine compounded into a topical formulation may inhibit keratinocyte proliferation and help with keratinizing disorders (ichthyosis, and possibly epidermal nevi and PPK)
  • N-acetylcysteine administered systemically can be help in mediating glutamate metabolism and help with neuropsychiatric disorders such as trichotillomania and neurodermatitis